Ingredients HE-X^TM

Chlorophytum Borivilianum (Safed Musli) Extract

What is it?

• Chlorophytum borivilianum (Safed musli) is considered as ‘white gold’ in the Indian system of medicine and it claimed the status of herbal alternative of “Viagra” devoid of any side effects.

• It is a rich source of over 25 alkaloids, vitamins, minerals, carbohydrates, proteins, steroid, polysaccharides and saponins. Ref: Pharmacognosy Research 2010; 2: 343–349.

What it does?

• Preclinical studies have shown that furostanol and spirostanol saponins in Safed musli possess testosterone-like effects, something that is necessary in the management of diabetes-associated sexual functionalities. Ref: Chinese Journal of Integrative Medicine 2009; 15: 448-53.

• The root extracts of Safed musli are known to be helpful in maintaining sperm characteristics and morphology. Ref: Clinical and Experimental Pharmacology & Physiology 2007; 34: 244-249 .

• Given the ability of Safed musli to increase the activities of other antioxidant enzymes and vitamin C, it is known for its application in the treatment of premature ejaculation and oligospermia. Ref: Journal of Ethnopharmacology 2013; 150: 421-41.

Withania Somnifera (Indian Ginseng) Extract

• Elevated stress levels have been known to increase the production and release of stress hormones, such as, epinephrine, norepinephrine and cortisol. Ref: American Journal of Men’s Health 2019, 1-15 , This ultimately results in testicular involution followed by significant drop in testosterone secretion, which leads to decreased libido and oligospermatogenesis (a decrease in the soldiers of your army!).

What it does?

• Ashwagandha, which is loaded with a number of alkaloids, ergostane steroids and amino acids, including tryptophan, centrally acting hypotensive agents, GABA- and serotonin agonists, is known to combat the plummeting stress levels. Ref: Journal of Medicinal Plants Research 2019, 13, 473-479.

How it works?

• Clinical trials on Ashwagandha have revealed its ability to reduce the serum levels of the stress hormone: cortisol, thus, exhibiting the anti-stress activity. Ref: Medicine 2019 98, 37: e17186.

• Alanine has a protective role against oxidative stress and can reduce lipid peroxidation and thus increase sperm concentration and motility. Ref: Evidence-Based Complementary and Alternative Medicine 2011 Volume 2011, Article ID 576962 Fortunately, Ashwagandha has been shown to increase alanine concentration in semen.

• Moreover, Treatment with Ashwagandha extract has been reported to improve the levels of testosterone and dehydroepiandrosterone (DHEA) and, thereby, libido among aged, infertile men .

Trigonella Foenum-Graecum (Fenugreek) Seed Extract

What it does?

• Trigonella foenum-graecum (Fenugreek) seed extract is known as a safe and effective treatment for reducing symptoms of possible androgen deficiency. It improves sexual function and increases serum testosterone in healthy middle-aged and older men. Ref: World Journal of Mens Health 2018, 36: 230–238.

• The Saponins present in fenugreek seeds are important precursors for the synthesis of testosterone and therefore, fenugreek extracts have been shown to increase the desire and sexual function. Ref: Phytotherapy Research 2011, 25, 1294-1300.

• Fenugreek seeds have also been shown to have significant positive effect on the spermatogenesis, thus can be used to treat infertility due to oligospermia. Ref: Kenkyu Journal of Pharmacy Practice & Health Care 2018, 4:1-3.

How it works?

• Clinical trials show that saponins in Fenugreek exert their androgenic effects by augmenting androgen receptor levels in the cells and by improving body’s sensitivity to androgens like testosterone. Ref: Critical Reviews in Food Science and Nutrition, 2020, 60, 2342-2352 .

Allium Sativum (Garlic) Extract

What it does?

• Garlic extract contains the active and stable component S-allylcysteine, which has been linked to stimulate the intracellular nitric oxide and hydrogen sulphide production, increasing the blood flow to penis, and can be helpful to treat erectile dysfunctions. Ref: Phytomedicine. 2017;24:56-61]

• Garlic has been reported to contain phytoestrogens, which have a direct effect on testosterone production, thereby stimulating the sexual cells and sex hormones.

How it works?

• Sulfur compounds in garlic, with a direct effect on the metabolism of caspase-3, cytochromes P450 (CYPs) and glutathione S-transferase, have a protective effect on testicular performance, consequently, improving spermatogenesis. Ref: Journal of Herbmed Pharmacology 2018, 7, 306-312;.